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William Pettit has worked in a variety of roles in the healthcare field since 2013. In 2013, they worked as a Research Analyst at Widnes Vikings RLC, where they analyzed data collected by the medical staff and presented their work at the British Association of Sports and Exercise Medicine annual conference. In 2014, they worked as Media Manager for SEMsoc (The Sports and Exercise Medicine Society), organizing and promoting lectures and events. From 2015 to 2016, they worked as a Foundation Doctor at Epsom and St Helier University Hospitals NHS Trust and Medway NHS Foundation Trust. In 2017, they worked as a Product Owner and Business Growth at Pando, where their goal was to connect healthcare teams around the world. Since 2018, they have been working as a Radiology Registrar and NHS Clinical Entreprenur Fellow at NHS England.

William Pettit attended Blundell's School from 2002 to 2009. William then went on to The University of Manchester, where they earned an MBchB in Medicine from 2010 to 2015.