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Jennifer Caldwell began their career in 2006 as a Research Assistant at Queens University of Charlotte's Chemistry Department. In this role, they were awarded a research grant from the National Science Foundation and conducted research with a Fourier Transform Nuclear Magnetic Resonance spectrometer. In 2007, they took on an Intern role at Emergency Medicine Clinical Research at Carolinas Medical Center. In 2008, they joined Harrison Hayes as a Corporate Development Director and Senior Analyst. At Harrison Hayes, they worked on forging innovation strategies, developing and ideating new products and businesses, and accelerating their path to market.

Jennifer Caldwell attended Queens University of Charlotte from 2005 to 2008, where they earned a Bachelor of Science in Biochemistry and Physical Sciences. Jennifer is currently enrolled at Columbia University, studying Visual Arts.