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Shireen Ong has been working in the business industry since 2008. Shireen began their career as a Senior Professional Medical Representative at GlaxoSmithKline Malaysia. In 2009, they moved to GlaxoSmithKline Singapore, where they served as an Associate Product Manager, Product Executive, and Account Specialist. In 2015, they joined Takeda Pharmaceuticals as a Product Manager. In 2016, they joined MSD as a Sales Manager for Hospital Acute Care and Business Manager, where they were awarded the Asia Pacific Region Award Best Executed Account Plan for 1H 2020 and Best Persona Understanding & Customer Journey for 1H 2020. In 2021, they moved to Oracle as a Regional Sales Manager for ASEAN, Healthcare & Life Sciences. Finally, in 2022, they joined Gurobi Optimization as an Account Director, with the goal of bringing the world's best optimization solver to customers in ASEAN & Taiwan.

Shireen Ong's education history includes a Bachelor of Science in Medical Bioscience from Monash University Malaysia (2004-2007), a Bachelor's Degree from Chong Hwa Independent High School (1992-1997), and SJK (C) Chung Kwok (1992-1997).