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William Leong has held various positions in the pharmaceutical industry over the past 30 years. In 1990, they began their career as a Senior Development Fellow at Schering-Plough Research Institute. In 2009, they moved to Celgene as Senior Director, Head of Process Chemistry. In 2014, they became Executive Director, Head of CMC at Newron Pharmaceuticals SpA. In 2018, they were appointed Senior Vice President, Technical Operations at Complexa Inc. In 2020, they took on the role of Vice President, CMC at Kymera Therapeutics. Currently, they are the Executive Vice President, Head of CMC at Gilgamesh Pharmaceuticals.

William Leong has attended four universities: University of California, Davis, Iowa State University, and University of San Francisco (twice). No degrees or fields of study were specified.