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Colin Melville has a diverse and extensive work experience in the field of medical education and leadership. Colin has held various positions throughout their career, including Visiting Professor at Anglia Ruskin University, Director at GMC Services International, and Medical Director and Director of Education and Standards at the General Medical Council. Colin has also served as Honorary Consultant in Intensive Care Medicine at University Hospitals of Morecambe Bay NHS Foundation Trust and NHS - University Hospitals Coventry and Warwickshire NHS Trust. Furthermore, Colin has held academic positions, such as Hon Professor at The University of Manchester and Head of Lancaster Medical School at Lancaster University. Colin has also been involved in medical education at the Royal College of Physicians and the University of Warwick. Throughout their career, Colin has demonstrated a commitment to medical education and standards, as well as a passion for research and development in critical care medicine.

Colin Melville attended Eltham College from 1971 to 1977. However, there is no information regarding their degree or field of study during this period. Later, from 1978 to 1983, they pursued Medicine at The University of Sheffield, where they earned an MB ChB degree.