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Elena Zotenko started their work experience in 2007 as a Postdoctoral Fellow at the Max Planck Institute for Informatics, where they worked until September 2010. Elena then joined the Garvan Institute of Medical Research in October 2010 as a Bioinformatics Research Officer, and their role there is still ongoing. In 2017, they joined Guardant Health as a Bioinformatics Scientist, and they are currently working in that position.

Elena Zotenko pursued their education in the field of Computer Science. Elena completed their Bachelor of Science (B.Sc.) degree at Tel Aviv University from 1994 to 1998. Following this, they furthered their studies at the University of Maryland, where they obtained their Ph.D. in Computer Science from 2001 to 2007.