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Muriel Defrance has worked in various finance-related roles throughout their career. Muriel started in Ernst & Young as a Senior Manager in 1998, where they remained until 2006. Afterward, they joined GE Capital, holding several positions such as Benelux Controller, Finance Integration Leader, and Compliance Controller. In 2010, they became the Regional Leasing Controller at GE Capital. In 2012, Muriel joined Owens Corning as the US GAAP Finance Manager for Europe and later became the EU FP&A Leader until 2020. Muriel'smost recent position is at Etex, where they are currently the Head of Finance Business Partnering Operations.

Muriel Defrance earned a Bachelor's degree in Economic and Commercial Sciences with a focus on Finance from HEC Liège between 1994 and 1998. Muriel later pursued a Post graduate degree in auditing and accounting expertise at Institut Cooremans from 2000 to 2001. Prior to that, they attended Collège Saint Barthélemy in Liège from 1987 to 1993, though the specific degree or field of study is not mentioned.