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Samiksha S. has had a diverse range of work experiences. Samiksha started their career at Unitech systems in 2012, where they worked as a Narrative writer and/or Reviewer, focusing on Pharmacovigilance and SAE narrative writing. Samiksha was also responsible for reviewing written narratives and tracking quality, while providing support for monthly team analysis. Samiksha then moved on to Thyrocare Technologies Ltd. in 2017, where they worked as a Content Writer. Their responsibilities included being the custodian of all content for the company's website, app, blog, delivery box, brochure, pamphlets, marketing collateral, and social media pages. Samiksha also enforced communication guidelines and ensured brand tonality in all communications. In 2018, Samiksha joined Testbook.com as a Senior Content Writer. Samiksha held this role until 2020, during which they contributed to the creation of high-quality content for the company. Most recently, Samiksha joined EdCast as a Senior Content Analyst in October 2020.

Samiksha S. obtained a M.Tech degree in Biotechnology from Dr. D.Y. Patil College for Biotechnology and Bioinformatics, which was completed from 2006 to 2008. Prior to that, they completed a Bachelor of Science (BS) degree from Mumbai University Mumbai, although the specific years are not provided. In addition to their formal education, they have obtained additional certifications. Samiksha completed the PGDDS C24 Course 1 LOA from upGrad in February 2021 and obtained the Google Analytics certification from Google in August 2020.