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Jake Leonard has worked in a variety of roles since 2010. In 2010, they worked as a Courtesy Clerk at Albertsons. In 2011, they worked as an Executive Assistant at Sorensen Wealth Management. In 2013, they were a Manager at the University of San Diego Finance Department. In 2014, they were an Analytical Chemist at Pfizer. From 2016 to 2018, they worked at Regulus Therapeutics as a Research Associate and Research Associate II. From 2018 to 2020, they worked at Catalent Pharma Solutions as a Pharmaceutical Chemist II, Associate Project Manager, and Project Manager. Currently, they are a Senior Manager of Nonclinical Operations at Arena Pharmaceuticals, Inc. and a Senior Manager of Operations at DTx Pharma.

Jake Leonard obtained their High School Diploma from Westlake High School between 2008 and 2012. Jake then attended the University of San Diego, where they earned a Bachelor of Science in Biochemistry between 2012 and 2016. In May 2019, they obtained a Green Belt Certification from MoreSteam.