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Marie Brayer has held a variety of roles in the tech industry since 2015. Marie began as a Business Angel in various tech companies such as Silvr and Mansio. In 2016, they co-founded TalentLetter, a start-up helping other start-ups recruit talented people. In 2017, they joined the board of Inato, a company helping life science companies accelerate recruitment in clinical trials. In 2020, they joined the board of Descartes Underwriting. In 2021, they became a Partner at Fly Ventures, a specialized VC for technical founders, and a Lead Seed Investor in Corrily, Matcha, and Palisade Inc. Additionally, they joined the board of Kili Technology.

Marie Brayer completed their Master of Science (MS) in Entrepreneurship/Entrepreneurial Studies at HEC Paris from 2011 to 2012. Prior to that, they obtained their Diplôme d'Ingénieur in Information Technology from IMT Atlantique from 2007 to 2011.