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Professor Wahl is the Elizabeth Mallinckrodt Professor, Chairman of the Department of Radiology and Director of the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St Louis.

Professor Wahl is recognised as a world leader in the field of targeted radiopharmaceuticals for diagnosing and treating cancer. With an emphasis on PET and multi-modality imaging, such as PET-CT, his work enables precision diagnosis of a broad array of human cancers and other serious diseases. Professor Wahl is one of the inventors of radio-immunotherapy of lymphoma, which is a combination of radiotherapy and immunotherapy that facilitates targeted treatments. He has also been an inventor of a number of FDA approved medical devices, such as radionuclide guided biopsy.

Professor Wahl holds 18 radiology patents and has published more than 450 peer-reviewed scientific papers and several books. He has served as a chairman of the American Board of Nuclear Medicine (ABNM), president of the Institute for Clinical PET (ICP) program, refresher course chair for Radiological Society of North America and on multiple NIH study sections. He was elected as a member of the US National Academy of Medicine in 2015. Most recently, Professor Wahl was elected 2021-22 president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).