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Sima Jalili has extensive work experience in the art industry. Sima is currently working as the Senior Vice President and Director of Gallery and Operations, West Coast at Christie's since 2021. Prior to this, they held various roles at Christie's including Vice President and Regional Managing Director from 2018 to 2020, Vice President and Head of Sale Management from 2016 to 2018, Associate Vice President and Business Manager from 2013 to 2016, and Administrative Manager from 2010 to 2013. Sima also worked at Atelier4 as a Registrar from 2007 to 2010, and at Chelsea Restoration Associates, Inc. as a Studio Manager from 2004 to 2007.

Sima Jalili obtained a Master of Arts (MA) degree in Museum Studies from New York University. Prior to that, they earned a Bachelor of Arts (BA) degree with Honors in Art History and a minor in Business from the University at Albany, SUNY.