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Patrick Herendeen's work experience includes roles as an Adjunct Professor at Northwestern University since July 2008 and as a Senior Director of Systematics and Evolutionary Biology at the Chicago Botanic Garden since July 2008. Patrick also worked as a Program Director at the National Science Foundation from August 2006 to June 2008, and as an Associate Professor at George Washington University from 1997 to 2008.

Patrick Herendeen earned their PhD in Botany from Indiana University Bloomington, completing their studies between 1985 and 1990.