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Johannes Irsch has extensive work experience in scientific and medical affairs. Johannes started their career at Miltenyi Biotec in 1998, where they held various roles including Technical Marketing Manager, Application Development Manager, Clinical Product Manager, and Clinical Marketing Manager. In 2006, they moved to Cerus and took up the position of Director of Scientific Affairs for Europe. Johannes was later promoted to Senior Director of Scientific Affairs for Europe and eventually became the Senior Director of Global Scientific and Medical Affairs in August 2019.

Johannes Irsch pursued their education and achieved a significant milestone during the period from 1984 to 1997. Johannes attended the University of Cologne and obtained a degree in Biologie. Johannes successfully completed their doctoral studies, earning the honorific "Dr. rer. nat."