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June Guan began their work experience in 2001 as a Research Associate at Johnson & Johnson. June then transitioned to TIAA-CREF in 2004 as an Associate Actuary. In 2005, they joined MetLife as an AVP & Actuary, where they were responsible for developing and supporting hedging strategies and maintaining insurance and investment models. June has been with MetLife until December 2021. In 2017, June Guan joined Brighthouse Financial as the Head of Strategic Analysis.

June Guan earned a Master's degree in Organic Chemistry from Brigham Young University, from 1998 to 2000. Prior to that, they completed a Bachelor of Science (BS) degree in Chemistry and Economy from Peking University, from 1994 to 1998.