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Simrat Reen started their work experience in April 2011 as an Administrator at Kemi Laboratories Pvt. Ltd. They then worked as a Sr. Manager - Guest Experience at Target from March 2013 to April 2015. From April 2015 to April 2016, they held the position of Assistant General Manager at Bed Bath & Beyond. Simrat then joined Coach as an Associate Store Director from April 2016 to February 2020. They then worked at Acuity Insights, starting as a Customer Success Manager from February 2020 to October 2020. They progressed to become the Manager of the Customer Success Team (USA) from October 2020 to December 2021, and then served as a Senior Manager of Customer Success from October 2021 to June 2023. Currently, Simrat is the Manager of Scaled Customer Success at BioRender, starting from June 2023.

Simrat Reen completed a Certificate in Business Analysis at the University of Toronto Mississauga in 2018. Prior to that, from 2009 to 2011, they pursued a Master's Degree in Double Masters in Biotechnology and Commerce at Macquarie University. Before that, from 2005 to 2008, Simrat Reen obtained a Bachelor's Degree in Biotechnology from Panjab University. It is also mentioned that they have a Master of Science (MS) degree in Biotechnology and Commerce from Macquarie University, but the start and end years are not specified.