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Marcella is the president of BioNews Clinical where she is involved in every facet of the work process that connects patients in our rare disease communities with ongoing clinical trials. As a creative builder and change agent, her mission is to promote a human-centered healthcare system built on empathy and radical collaboration: where patients are integral contributors to the collective efforts aimed at advancing the understanding and cure of rare and chronic diseases. Over the past 12 years, across multiple organizations, including Harvard Clinical Research Institute, Science 37, and monARC Bionetworks, she led a multitude of patient-centric projects spanning from patient-powered trial design, patient recruitment and engagement for traditional and virtual/remote clinical trials, patient community development, growth, and engagement through co-creation with peers. She serves as an adviser to pharmaceutical companies, nonprofit organizations, healthcare innovation accelerators and startups for topics related to effective patient engagement in clinical trials and co-creation with patients.