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Kara Puopolo has a diverse work experience that spans various industries. Kara has a significant background in the pharmaceutical field, with their most recent role being as the Director of Supply Chain & Logistics at AVEO Oncology. Prior to this, they held positions of increasing responsibility at AVEO, including Associate Director, Senior Manager, Manager, and Technical Coordinator in the Investigational Supply Operations department. Before joining AVEO, Kara worked as an Administrative Assistant in Pharmacovigilance. Kara also has experience in the legal field, having worked as a Paralegal at Harmon Law Offices, P.C. Additionally, Kara gained practical knowledge through an internship as a Legislative Intern at the Commonwealth of Massachusetts.

Kara Puopolo attended Kamehameha Schools Kapalama Campus, where they completed their high school education in the year 2006. Following that, they pursued a Bachelor's degree in International Relations & Religion Studies at Lehigh University, which spanned from 2006 to 2010. However, specific details about their field of study are not provided.