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Simon Diez has worked for three organizations, starting with Columbia University in the City of New York in 2015 as a Graduate Research Assistant. From 2021 to 2022, they were a Postdoctoral Scholar at the University of Washington. Currently, they are employed as a Scientist I, Genetic Design and Build at Arzeda.

Simon Diez obtained their Bachelor of Science in Biology, General from the University of South Carolina in 2015. Simon then went on to pursue their Master of Arts in Microbiology and Immunology from Columbia University, which they completed in 2017. Following this, they earned their Master of Philosophy in Microbiology and Immunology from Columbia University in 2019, and is currently in the process of completing their Doctor of Philosophy in Microbiology and Immunology from Columbia University, which they are expected to complete in 2021.