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Nicole Mascuch has worked in a variety of roles since 2005. Nicole began their career as a Sales Account Executive at Quality Distribution Network, LLC in 2005. In 2007, they moved to PDI as a Practice Management Consultant. In 2008, they became an Administrative Assistant at Brooklake Country Club. In 2009, they took on the role of Group Outing Consultant/Golf Concierge at Crystal Springs Resort. In 2010, they were an Executive Assistant at Edifice, now part of SPS Commerce, Inc. In 2011, they attended Sussex County Community College. In 2014, they became a Sr. Administrator/Executive Assistant at CooperGenomics. In 2017, they became an Administrative Services Manager and Executive Assistant at Lumanity. Finally, in 2023, they became the Executive Assistant to the Chief Executive Officer at Apertura Gene Therapy.

Nicole Mascuch attended Fairleigh Dickinson University from 2001 to 2005, where they obtained a Bachelor's degree in Hotel Management.