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Zeng Kai has been working in the technology industry since 2008. From 2008 to 2012, they worked as an Image Reconstruction Algorithm Scientist at GE Global Research, where they developed technology for Medical Imaging CT systems and had expertise in both analytical and statistical Image Reconstruction development. Zeng also led projects for cone-beam algorithm development and fully 3D iterative reconstruction algorithm development. In 2012, they became the Director of Technology at Shenzhen Anke High-tech Co., Ltd.

Zeng Kai completed their Bachelor's degree in Engineer Physics from Tsinghua University in 2002. Zeng then went on to complete their Master's degree in the same field at Tsinghua University in 2004. In 2007, they completed their Ph.D. in Medical Imaging from the University of Iowa.