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Stephan has about 20 years pharmacological R&D experience. Previously he was assistant professor and Principle Investigator Pharmacology at the Academic Medical Center in Amsterdam, working on the pharmacology and pathophysiology of sphingolipids. He was involved in biochemical pharmacology and translational research in a variety of therapeutic areas (cardiovascular, CNS, metabolic and urology). He has published more than 55 scientific papers in peer reviewed scientific journals. From 2014-2019 he was professor of Life Sciences at Fontys University of Applied Sciences, Eindhoven The Netherlands.

In the past eight years Stephan was involved in drug development within biotech industry. He is currently also Chief Scientific Officer at Okklo Life Sciences and Director Business Development at Brightlands Maastricht Health Campus (Maastricht University, the Netherlands).