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Oeke Brüning has a diverse work experience in the field of quality control and pharmaceuticals. From 2013 to 2020, they worked at Apotex Nederland BV, starting as a Junior QC Technician and progressing to become a Senior QC Technician and eventually a QC Supervisor, responsible for subject matter support and supervision of technicians running various tests. In 2020, they briefly served as the Interim QC Manager at the same company. From 2020 to 2023, Oeke worked as the Quality Control Laboratory Supervisor at InnoGenerics. Currently, in 2023, they are working as a QA Data Reviewer at Akorn Pharmaceuticals. Prior to their pharmaceutical experience, Oeke also had experience working abroad, including being a divemaster in Indonesia and working on farms and wineries in Australia. Oeke also worked as a Product Developer at Sara Lee Household & Body Care Research in 2007.

Oeke Brüning attended Rotterdam University of Applied Sciences from 2002 to 2007, where they earned a Bachelor's degree in Analytical Chemistry.