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Jan Karoll began their work experience in 1984 as an Assistant Administrator/Program Director/Nurse Manager at Tidewater Psychiatric Institute. They then worked as a Hospital Administrator at the same institute from 1991 to 1995. In 1995, they joined Merck as an Osteoporosis Specialty Representative and later became an Oncology Specialty Representative, staying with the company until 2018. From 2018 to 2021, they worked at Clovis Oncology as a Key Account Manager. Currently, they are working at ADC Therapeutics as a Hematology Therapeutic Specialist and have recently transitioned to the role of Associate Director Hematology Strategic Accounts.

Jan Karoll earned a Bachelor's degree in Nursing from the University of North Carolina at Charlotte. Jan also obtained certification as a Registered Nurse in Virginia. However, specific information regarding the start year, end year, institution, month of certification, and year of certification are not provided.