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Isobel Byrne has a diverse work experience history. Isobel began their professional career as a Tutor at the International School Basel in 2015, where they worked until February 2016. Following this, Isobel worked as a Barmaid and Waitress at Key West from April to September 2016, gaining valuable skills in customer service and managing high-stress environments. In 2017 and 2018, Isobel worked as a Summer Student at Roche. In 2019, they interned as a Digital Health Intern at Roche and later joined Calastone, where they held the roles of Analyst and Associate. Most recently, Isobel joined ActiveViam in February 2021 as a Solution Engineer.

Isobel Byrne completed their primary education at Withington Girls' School from 2008 to 2013, where they obtained their GCSEs. Following this, they attended the International School Basel from 2013 to 2015, where they pursued the International Baccalaureate. Isobel then went on to enroll at UCL from 2016 to 2019, where they pursued a Bachelor of Science degree in Theoretical and Mathematical Physics.