Dr. Mamonkin is a leading research expert in developing new therapeutic tools to treat hematologic malignancies and solid tumors using adoptive cell therapy. He currently serves as an Assistant Professor in the Center for Cell and Gene Therapy and maintains academic appointments in the Department of Pathology and Immunology at Baylor College of Medicine in Houston, Texas. Dr. Mamonkin directs a laboratory that focuses on investigating the mechanisms and effects of CAR signaling in therapeutic T cells and developing new engineered approaches using genome editing and synthetic biology to enhance cell therapy of aggressive hematologic malignancies. He oversees the clinical translation of investigational therapies through cGMP manufacturing to the clinic and serves as a co-principal investigator on several ongoing and upcoming clinical trials of CAR T cells in hematologic malignancies at Baylor College of Medicine.
Dr. Mamonkin received his Ph.D. in Immunology at Baylor College of Medicine studying the transcriptional regulation of T-cell differentiation in response to bacterial infection and completed his postdoctoral training with Dr. Malcolm Brenner at the Center for Cell and Gene Therapy, Baylor College of Medicine.