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Paul de Villèle has a diverse work experience. Paul began their career as a Pharmacy Intern at Hopital Foch in October 2016 and worked there until March 2017. Afterwards, they joined Voluntis and held various roles, including an internship in Medical Affairs from April 2017 to September 2017, an apprenticeship in Real-World Evidence from September 2017 to August 2018, and finally a position as a Real-World Evidence Research Analyst from September 2018 to April 2020. Currently, Paul is working at Withings, where they started in May 2020 as a Medical & Research Partnerships Manager and is now serving as the Head of Clinical Affairs since July 2023.

Paul de Villèle earned a Doctor of Pharmacy (PharmD) degree in Pharmaceutical Industry from Université Paris Cité from 2011 to 2018. Paul also pursued a Master 2 (M2) degree in Medical Devices at Paris-Sud University from 2017 to 2018, and completed a Master's degree in Public Health at Université Paris Cité from 2014 to 2016.