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Lou Reese has an extensive and diverse work experience. Lou is currently serving as the Executive Chairman and Co-Founder at VAXXINITY and COVAXX respectively, both since 2020. Prior to this, they were a Co-Founder at United Neuroscience in 2015 and Give to Cure in 2013. Lou has also held the position of Co-CEO at United Biomedical, Inc. (UBI) starting from 2012. Additionally, Lou Reese founded the Jack Green Group in 2011.

Lou Reese attended the University of Pennsylvania from 2000 to 2004, where they obtained a Bachelor's degree in Urban Studies/Affairs. Following this, from 2007 to 2009, they attended Columbia University to pursue an MBA degree.