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Paul is Harrap Professor of Pharmacology and Therapeutics at the Institute of Cancer Research (ICR), as well as the former Head of the Division of Cancer Therapeutics Division of Cancer Therapeutics and former Director of the Cancer Research UK Cancer Therapeutics Unit from 1997-2016.

A leader in the field of molecularly targeted cancer drugs, he is a Fellow of the Royal Society, Academy of Medical Sciences, the Royal Society of Medicine, the Royal Society of Chemistry and the Royal Society of Biology and is a Cancer Research UK Life Fellow. Paul's research focus is the discovery and development of cancer drugs that exploit our knowledge of the cancer genome and cancer biology and his passion is personalised medicine.