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Rami Kasterstein has worked in a variety of roles since 2016. In that year, they joined LawGeex as a Board Member. In 2017, they joined Raft Technologies as a Board Member, FlipOS as a Founding Board Member, and Spacemesh as a Co-Founder and Board Member. In 2018, they joined OpenWeb as an Investor and Advisor. In 2019, they joined Sorbet as a Co-Founder and Board Member. In 2021, they joined Ikko Health as a Co-Founder and Board Member. In 2022, they joined Ownera as a Board Member and Agora Labs as a Co-Founder and Board Member. Additionally, since 2016, they have been the Managing General Partner of Scale-Up Venture Capital, a growth stage fund investing around the world.

Rami Kasterstein received a B.Sc in Mathematics and Computer Sciences from Tel Aviv University between 1984 and 1987. Rami then went on to earn an M.Sc in Computer Sciences from the Weizmann Institute between 1991 and 1992.