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Jeffrey Grossi's work experience includes serving as the Chief of Government Relations at Sheppard Pratt Health System since 2019. Prior to that, they worked at the University of Maryland Baltimore as a Senior Government Affairs Specialist from 2016 to 2018. From 2009 to 2016, Grossi held various roles at The Johns Hopkins University, including Director of Federal Affairs and Associate Director of Federal Affairs. Jeffrey also worked as a Research Policy Analyst at Johns Hopkins University from 2006 to 2009. Before that, they were a Regulatory Affairs Specialist at Johns Hopkins Medicine from 2004 to 2006, where they had experience with human subjects research regulations, clinical trials, and Medicare regulations related to research billing.

Jeffrey Grossi completed their primary education at Loyola Blakefield from 1989 to 1993. Jeffrey then pursued a Bachelor of Arts degree in Economics at the University of Maryland from 1993 to 1998. Following their undergraduate studies, Jeffrey attended the University of Maryland Francis King Carey School of Law from 1998 to 2001, where they obtained a Juris Doctor degree.