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Angela Shen is currently Vice President, Strategic Innovation Leaders at Mass General Brigham and has served as Chief Medical Officer (CMO) at multiple venture-backed biotech startups including Walking Fish, Arcellx, NKarta, Arvinas, and acting CMO of Tizona. Dr. Shen has led oncology programs in a variety of pharmaceutical settings for over 15 years through all stages of drug development including IND filings, first-in-human trials, registrational trials, and NDA/BLA filings. While working in oncology clinical development at Novartis, Dr. Shen was extensively involved with in-licensing University of Pennsylvania’s CAR-T technology. She assembled and led the clinical team responsible for designing and launching the industry’s first multi-site, registration CAR-T trial, which resulted in the approval of Kymriah® (CTL019, CART-19). Prior to that, Dr. Shen made key contributions to the development of several oncology drugs within Novartis, Exelixis, and Johnson & Johnson that were subsequently approved.