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Leslie Zanetti has a diverse work experience spanning over several decades. Leslie began their career as a Pharmacy Specialist in Cardiology at St Joseph Mercy Hospital in 1987, where they worked until 1996. Leslie then transitioned to Henry Ford Health System where they continued their role as a Pharmacy Specialist in Cardiology until 2001. In 2001, Leslie joined Sanofi as an Area Medical Manager and held various roles within the company, including Outcomes Liaison and Director of Diabetes Regional Medical Liaisons - MidAtlantic Region. In 2018, they joined Sarepta Therapeutics where they currently serve as the Senior Director of Medical Managed Care, Team Lead.

Leslie Zanetti attended The University of Michigan from 1980 to 1986, where they earned a PharmD degree in Pharmacy.