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Bryan Luce has a diverse work experience in the field of healthcare and research. Bryan started their career at MEDTAP International in 1983, where they held multiple roles including Founder, Chairman, and CEO. Bryan was responsible for the company's growth and success until 2003. Following this, Luce joined United BioSource Corporation and served as a Senior VP in Science Policy. In 2003, they became a Senior VP at the same company and held this position until an unspecified date. In 2013, Luce joined Patient-Centered Outcomes Research Institute (PCORI) as the Chief Science Officer. Lastly, Luce also worked at UBC as an SVP, however, the specific details regarding their role and tenure are not provided.

Bryan Luce obtained their Ph.D. in Health Services Research from UCLA Fielding School of Public Health, graduating between 1975 and 1979. Prior to this, Bryan completed their Bachelor of Science (BS) and also supplemented their studies with an MSPH and MBA from the University of Massachusetts Amherst. No specific years were provided for their time at the University of Massachusetts Amherst.