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DG

David J. Greenblatt

Advisor at OrphoMed

David J. Greenblatt, M.D. holds the Louis Lasagna, M. D., Endowed Professorship at Tufts University School of Medicine, and is a senior faculty member in the Graduate Program in Pharmacology & Experimental Therapeutics at the Sackler School of Graduate Biomedical Sciences at Tufts University. He also holds appointments as Professor of Psychiatry, Medicine, and Anesthesia, Tufts University School of Medicine. His research work focuses on the following areas: molecular and clinical pharmacokinetics/pharmacodynamics, genetic and environmental factors regulating drug metabolism by Cytochromes P450 and glucuronosyl transferases, and energy-dependent transport by P-glycoprotein and other transporters, mechanisms, consequences, and in vitro prediction of metabolic drug-drug interactions attributable to enzyme inhibition and induction, the effect of age, gender, body habitus, and dietary composition on drug disposition and response, drug interactions involving nutrients and natural substances, molecular and clinical determinants of ligand binding and pharmacodynamic response to centrally-acting drugs. He received his M.D. from Harvard Medical School.