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Mai Shiber began their career in 2013 as a Quality Assurance Specialist for Israeli Military Intelligence. In 2019, they joined Itamar Medical as a Clinical Trainer, where they trained doctors and medical staff from all over the world on a FDA approved device for assessing endothelial dysfunction. Mai also performed clinical testing with the device on patients in tertiary Israeli hospitals. In 2020, Mai joined Sheba Tel HaShomer City of Health as a Medical Researcher for the Arrow Project, a medical research excellence program. In this role, they collected data, performed statistical analysis, and wrote several papers. Mai currently works at Navina as a Senior Medical Analyst and Medical Analyst.

Mai Shiber attended Ariel University from 2019 to 2023, where they obtained a Doctor of Medicine - MD degree. Prior to that, they attended Technion - Israel Institute of Technology from 2016 to 2019, where they earned a Bachelor of Science - BS in Medicine.