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Dr. Wittenberg received training at Harvard, UC San Diego, Washington U., St. Louis, and the National Institutes of Health. His clinical and research interests are in neurorehabilitation, stroke, cerebral palsy, and movement disorders. He uses transcranial magnetic stimulation, functional imaging, and rehabilitation robotics to study the recovery of motor function.

He has a tenured appointment as a Professor in the Department of Neurology and is a Neurologist/Researcher in the Veterans Affairs Pittsburgh Healthcare System. Secondary appointments are also pending. He is Director of the Laboratory for Research on Arm Function and Therapy (RAFT), one of the Rehab Neural Engineering Labs. He arrived in Pittsburgh in 2018 as the outgoing Director of the VA Maryland Exercise and Robotics Center of Excellence.