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Sharon Shacham is an accomplished entrepreneur and leader with extensive experience in both the biotechnology and climate technology sectors. Currently, Sharon serves as Co-Founder and Managing Director of E44 Ventures, which focuses on supporting innovative solutions to climate challenges. Additional roles include Advisory Board member at Phelas, Board Observer at Gigablue and Carbonade, and Board Member at AgriPass and Acrivon Therapeutics, all dedicated to advancing sustainability and novel drug development. Sharon founded Karyopharm Therapeutics Inc., emphasizing the development of first-in-class cancer therapies, and is actively involved in Sporos Bioventures and ProtAI as a Scientific and Clinical Advisor and Scientific Advisor, respectively. Educational credentials include a PhD in Biochemistry and Computational Biophysics and an MBA in Information Systems, both from Tel Aviv University.