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Amie Williams-Frame has extensive work experience, starting in 2008 as a Clinical Research Associate at Indiana University Bloomington. Amie then worked at the Regenstrief Institute, Inc., as a Research and Development Program Manager from 2010 to 2015. Following that, they returned to Indiana University Bloomington and held the position of Proposal Development Specialist from 2015 to 2018. From 2018 to 2022, they served as Research Faculty and Director of Commercialization Grant Development at Indiana University Bloomington. Currently, they are the Managing Director at McAllister & Quinn starting from December 2022.

Amie Williams-Frame's education history begins in 2000 when they attended Indiana University Bloomington. Amie completed their Bachelor of Science degree in Pre-Medicine/Pre-Medical Studies/Biology in 2004. In 2005, they attended Franklin College and earned a Bachelor of Arts degree in Chemistry the following year.

Moving forward, Amie pursued further education at Indiana University School of Medicine from 2006 to 2009. During this time, they obtained a Master of Public Health (MPH) degree with a specialization in Epidemiology.

In addition to their academic achievements, Amie received certification as a Certified Clinical Research Professional (CCRP) from the Society of Clinical Research Associates (SOCRA), although the specific timeline for obtaining this certification is not provided.