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Leon Barzin has a diverse work experience spanning over multiple fields. Leon began their career as a Fisheries Program Analyst at the National Marine Fisheries Service in 1981 and later transitioned to become a Software Documentation Writer at Intelligent Designs in 1983. From 1984 to 1989, Barzin served as the Printed Projects Manager at Leading Edge, followed by their role as Director of Documentation at Leading Edge Products from 1983 to 1990. In 1991, they worked as the Electronic Publishing Manager at Nimrod Press. Barzin then moved on to the New England Journal of Medicine in 1992, where they served as the Director of IT until 2010. Simultaneously, they joined the Massachusetts Medical Society in 2011 as the Director of Health Information Technology and Manager of Digital Media, a position they currently hold. Throughout their career, Barzin has demonstrated expertise in various areas such as publishing workflow, vendor relations, and digital media technologies.

Leon Barzin completed their education in a chronological order. Leon obtained a High School Diploma in Liberal Arts and Sciences, General Studies, and Humanities from Millbrook School in 1968. Following this, they attended Hiram College from 1968 to 1972 and earned a Bachelor of Arts degree in English. From 1972 to 1974, Leon attended Université de Grenoble, where they pursued a 3eme degree in French. Leon then enrolled at the University of Oregon from 1977 to 1979 and obtained a Bachelor of Science degree in Biology. Finally, Leon completed a Master's program in Environmental Biology at the University of Oregon from 1980 to 1981.