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Megan O'Toole has worked in the medical industry since 1998, beginning their career as a Clinical Research at AGA Medical. Megan then worked as a Senior Clinical Manager at Anulex Technologies in 2011, and as a Clinical Study Manager at Uroplasty, Inc. in 2012. In 2010, they moved to St. Jude Medical (formerly AGA Medical) as a Clinical Research. In 2015, they joined Zyga as a Senior Clinical Manager, and then moved to RTI Surgical (formerly Zyga) as a Senior Manager, Clinical Affairs in 2018. Most recently, in 2020, they were a Senior Manager, Clinical Affairs at Surgalign (formerly RTI Surgical). In 2021, they began working as a Sr Manager, Clinical Operations at Lungpacer Medical, Inc.

Megan O'Toole holds a Bachelor of Science from Winona State University.