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John Maraganore

Advisor at Legend Biotech

Dr. Maraganore served as the founding CEO and Director of Alnylam Pharmaceuticals from 2002-2021, where he led the company through the approval and global commercialization of the first four RNA interference therapeutic medicines. At Alnylam, he developed the company’s value strategy, building over $25 billion in market capitalization throughout his tenure. He remains a member of the Alnylam Scientific Advisory Board.

Prior to joining Alnylam, Dr. Maraganore held a number of leadership roles at Millennium Pharmaceuticals, Inc., across M&A, strategy, and was responsible for the company’s oncology, and cardiovascular, inflammatory and metabolic diseases businesses. Before Millennium, Dr. Maraganore spent ten years at Biogen, Inc. in a number of business and clinical roles, where he led the discovery and development of ANGIOMAX® (bivalirudin). Prior to that, he was a scientist at ZymoGenetics, Inc. and the Upjohn Company.

Currently, Dr. Maraganore serves as a Venture Partner at Arch Venture Partners, a Venture Advisor at Atlas Ventures, a Senior Advisor at Blackstone Life Sciences, Executive Partner at RTW Investments, and as an Advisor at M28. He is Chair Emeritus of the Biotechnology Innovation Organization (BIO) and a member of the BIO board and its Executive Committee. In addition, he serves on the board of a number of public and private companies: Agios Pharmaceuticals, Beam Therapeutics, Kymera Therapeutics, ProKidney Corp, Takeda Pharmaceuticals; Aera Therapeutics (Chair), Aerium Therapeutics, Aitia (Chair), Hemab Therapeutics (Chair), Orbital Therapeutics (Founder and Executive Chair), and Versanis Bio.


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