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Yi Zhang has extensive experience in medicinal chemistry research. They began their career in 2007 at GNF, where they were a research investigator for five years before being promoted to research investigator II. In 2016, Zhang joined Syros Pharmaceuticals as a senior scientist in medicinal chemistry. After two years, they moved to Kymera Therapeutics, where they held several roles, including principal scientist, associate director, and currently director of medicinal chemistry.

Yi Zhang has a Doctor of Philosophy (PhD) degree in Organic Chemistry from Harvard University. Before that, they obtained a M.A. degree in Organic Chemistry from Princeton University.