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Prerna Vashisht has worked for several companies since 2014. Prerna began as an Intern at Ind-Swift Limited in 2014, followed by an Intern role at Indian Oil Corporation Limited in 2015. In 2017, they were a Summer Intern at H2M architects + engineers. In 2018, they were a Process/Project Engineer at UTB - United Technology, Inc. and an Inside Sales Engineer at Crane ChemPharma & Energy. Her current role is Operations Project Manager at iS CLINICAL, which they have held since 2021.

Prerna Vashisht holds a Master's Degree in Chemical Engineering from the University of Southern California, which they obtained between 2016 and 2018. Prerna previously earned a Bachelor of Technology (B.Tech.) in Chemical Engineering from Deenbandhu Chhotu Ram University of Science & Technology, Murthal(Sonepat) between 2012 and 2016. In 2020, they also obtained certifications in Learning Minitab and Process Improvement Foundations from LinkedIn.