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Annika Lee has a diverse work experience, beginning with a role as a Party Host at Jump!Zone in 2012. Annika then worked as a Cashier at Super Sundaes and Hansel 'n Griddle in 2012 and 2014, respectively. In 2015, they interned at The Janssen Pharmaceutical Companies of Johnson & Johnson, followed by a role as an Undergraduate Research Assistant at the University of Maryland in 2016. In 2017, they worked as a Crew Member at Chipotle Mexican Grill, and then as a Graduate Student and Graduate Teaching Assistant at the University of Wisconsin-Madison from 2018-2020. In 2021, they joined Invenra, where they have held the roles of Associate Scientist I and Senior Research Associate, as well as Associate Production Scientist at MilliporeSigma.

Annika Lee attended Hillsborough High School from 2010 to 2014. Annika then went on to the University of Maryland, where they earned a Bachelor of Science in Cell Biology & Genetics in 2017. In 2018, they began their Master of Science in Pharmaceutical Sciences at the University of Wisconsin-Madison and completed their degree in 2020.