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Priyanka B has work experience as a Technical Assistant at the University of Kerala from January 2016 to October 2016. Priyanka then worked as a Research Assistant at the Department of Genomics, Madurai Kamaraj University from December 2017 to July 2019. In 2021, they joined CSIR-NIIST as a Project Associate. Currently, they are working as a Bioinformatics Engineer at iNDX.Ai since July 2022.

Priyanka B began their education by completing a Bachelor of Science degree in Bioinformatics at Malankara Catholic College in Mariagiri, Kaliakkavillai, Kanyakumari Dist. from 2010 to 2013. Priyanka then went on to pursue a Master of Science degree in Computational Biology at the University of Kerala from 2013 to 2015. After obtaining their master's degree, Priyanka B decided to further their education and completed a Master of Philosophy degree in Bioinformatics and Computational Biology at the University of Kerala from 2016 to 2017.