Dr. Richard Frye is a Child Neurologist and Director of Autism Research at Arkansas Children's Hospital Research Institute. He is an Associate Professor in Pediatrics at the University of Arkansas for Medical Sciences, and Director of the Autism Multispecialty Clinic at Arkansas Children's Hospital. Dr. Frye is a well-recognized expert in the diagnosis and treatment of Autism Spectrum Disorders (ASD) and other developmental disorders. Over the past several years he has completed three clinical studies related to ASD, including an open-label trial examining the metabolic and behavioral effects of tetrahydrobiopterin, a clinical study of the metabolic and genetic characteristics of children with ASD and mitochondrial disease, and a clinical study on the prevalence of the folate receptor alpha autoantibody in children with ASD, as well as the response to leucovorin treatment in ASD children with the folate receptor alpha autoantibody. Dr. Frye received a B.A. from Long Island University and earned his MD/Ph.D. from Georgetown University. He completed a residency in Pediatrics at the University of Miami, followed by a residency in Child Neurology and a fellowship in Behavioral Neurology and Learning Disabilities at Harvard University/Children's Hospital Boston. He is board certified by the American Board of Pediatrics, and the American Board of Psychiatry and Neurology with Special Competence in Child Neurology. He is a national leader in autism research. He has authored numerous research publications and book chapters, and serves on several editorial boards of prestigious scientific and medical journals. He is a member of the American Academy of Neurology, American Academy of Pediatrics, International Society for Autism Research, and the Society for Neuroscience. Dr. Frye has a broad background including specific training in neurodevelopmental disorders, physiology, psychology, and biostatistics. He is fellowship trained in Behavioral Neurology and Psychology and has clinical expertise in the assessment, diagnosis, and treatment of children with ASD. As Director of Autism Research at the Arkansas Childrenās Hospital his goal is to develop an integrated autism program that includes a multi-specialty autism clinic, a translational research program focusing on biomarkers and clinical-trials, and a basic science program focusing on mitochondrial and redox metabolic metabolism.