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Simon Mwenda has held various roles in the past five years. In 2021, they began working as the Compliance Lead for Ilara Health. From 2018 to 2021, they worked as the RA assistant for Goodman Agencies. From 2016 to 2018, they worked as the Regulatory Affairs Officer for Evka Consultz, where they assembled, submitted, and managed regulatory submissions to support new products approval and existing products maintenance. Additionally, they worked on medical device submission, nutraceticals submission, approvals, and retention in the market, as well as pharma and non-pharma importation permits. From 2016 to 2018, they also held an Intern role at Laikipia County Government.

Simon Mwenda completed their Bachelor of Arts in Economics from Moi University between 2012 and 2015. Simon'sfield of study was Economics.