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Haiguo Wu has a wealth of work experience, beginning in 1997 when they were a Postdoctoral Fellow at Brigham and Women's Hospital, Harvard Medical School. Haiguo then worked at Genedata Inc. as a Senior Bioinformatics Scientist from 2001 to 2007 and at febit inc. as a Lead Bioinformatics Scientist from 2007 to 2011. From 2011 to 2012, they were an Informatics Tech Specialist at AstraZeneca R&D, followed by roles as a Healthcare Informatics and Senior Bioinformatics Scientist at ConvergeHEALTH by Deloitte from 2012 to 2015. From 2015 to 2020, they were a Director of Bioinformatics, Associate Director of Bioinformatics, and Senior Bioinformatician at WuXi NextCODE, and they are currently a Director of Bioinformatics at Genuity Science.

Haiguo Wu obtained their B.S. in Biochemistry from Nanjing University, their M.S. in Molecular Genetics from the Institute of Genetics, Chinese Academy of Sciences, and their Ph.D. in Molecular Biology from the University of Florida.