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The Healthcare Technology Assessment (HTA) Leaders team at Health Technology Assessment international (HTAi) comprises experts from various fields and countries who guide and shape the global agenda for health technology assessment. The team ensures rigorous standards and ethical considerations in HTA practices, promotes the integration of real-world evidence and artificial intelligence, and fosters patient and citizen involvement. They also provide specialized insights into public health, hospital-based HTA, and medical devices to inform policy and clinical decisions worldwide.